{"id":19346,"date":"2021-11-15T06:31:53","date_gmt":"2021-11-15T10:31:53","guid":{"rendered":"https:\/\/www.nutracapusa.com\/?page_id=19311"},"modified":"2022-01-02T11:34:27","modified_gmt":"2022-01-02T11:34:27","slug":"affron-crocus-sativus-saffron-extract","status":"publish","type":"page","link":"https:\/\/www.nutracapusa.com\/affron-crocus-sativus-saffron-extract\/","title":{"rendered":"Affron\u00ae (Crocus Sativus) Saffron extract"},"content":{"rendered":"

[vc_row css=”.vc_custom_1641123265974{margin-top: 20px !important;}”][vc_column][vc_column_text css=”.vc_custom_1636972309949{margin-bottom: 0px !important;}”]Overview Description<\/b><\/p>\n

Affron\u00ae<\/b> is a premium saffron ingredient standardized<\/b> to 3.5% Lepticrosalides\u2122, which is responsible for the beneficial properties and organoleptic properties of affron\u00ae. … Affron\u00ae genuine quality relies on local trusted sourcing, the selection of the Spanish species Crocus sativus L.<\/p>\n

https:\/\/www.gencorpacific.com\/ingredients\/affron<\/a><\/p>\n

Saffron Crocus (Crocus Sativus)<\/p>\n

Benefits<\/b><\/p>\n

Saffron can be used for menstrual cramps and regulation of premenstrual syndrome (PMS).\u00a0<\/b><\/p>\n

It can be used to prevent premature ejaculation and infertility<\/b>.<\/p>\n

Saffron has also been used as an aphrodisiac.<\/p>\n

It is the main ingredient in (alopecia) to help alleviate baldness<\/b><\/p>\n

It helps to reduce<\/b> blood pressure<\/b> as it has antihypertensive properties on the heart and or total peripheral resistance, or possibly both.<\/p>\n

Crocus Sativus has an anticonvulsant constituent<\/b>, safranal, which was evaluated in mice and showed reduced seizure duration, delaying the onset of tonic convulsions.<\/p>\n

Anti-genotoxic and cytotoxic effects of saffron suggest that saffron itself, as well as its carotenoid components of Crocus Sativus might be used as potential cancer chemopreventive agents.<\/b><\/p>\n

Indications show it has a potent stimulatory effect on \u03b22-adrenoreceptors, which is partially due to its constituent, safranal.<\/p>\n

A possible anti-histamine effect <\/b>on histamine receptors was also suggested.<\/p>\n

A study has indicated the efficacy of Crocus Sativus in the treatment of mild-to-moderate depression<\/b>.<\/p>\n

Saffron, crocin and crocetin, improved memory and learning skills <\/b>in ethanol-induced learning behavior impairments in mice and rats.<\/p>\n

Studies have shown the potential of saffron as an antioxidant.<\/b><\/p>\n

Crocus Sativus exhibited antinociceptive effects <\/b>in chemically induced pain tests as well as acute and\/or chronic anti-inflammatory activity. This might be due to the presence of flavonoids, tannins, anthocyanins, alkaloids, and saponins.<\/p>\n

Forms and Sources<\/b><\/p>\n

Affron\u00ae Saffron Crocus (Crocus Sativus)<\/p>\n

Side Effects and Interactions<\/b><\/p>\n

Some possible side effects include dry mouth, anxiety, agitation, drowsiness, low mood, sweating, nausea or vomiting, constipation or diarrhea, change in appetite, flushing, and headache. Allergic reactions can occur in some people.<\/p>\n

How to Label<\/b><\/p>\n

Affron\u00ae (Crocus Sativus)<\/p>\n

Research & Studies (References)<\/b><\/p>\n

affron \u00ae a novel saffron extract (Crocus sativus L.) improves mood in healthy adults over 4 weeks in a double-blind, parallel, randomized, placebo-controlled clinical trial<\/p>\n

affron\u00ae increased mood, reduced anxiety and managed stress without side effects, offering a natural alternative to standard treatments.<\/p>\n

https:\/\/pubmed.ncbi.nlm.nih.gov\/28735826\/<\/a><\/p>\n

affron \u00ae, a standardised extract from saffron (Crocus sativus L.) for the treatment of youth anxiety and depressive symptoms: A randomised, double-blind, placebo-controlled study<\/p>\n

The administration of a standardised saffron extract (affron\u00ae) for 8 weeks improved anxiety and depressive symptoms in youth with mild-to-moderate symptoms, at least from the perspective of the adolescent. However, these beneficial effects were inconsistently corroborated by parents.<\/p>\n

https:\/\/pubmed.ncbi.nlm.nih.gov\/29510352\/<\/a><\/p>\n

Crocus sativus<\/i> L.: A comprehensive review<\/p>\n

Crocus sativus L<\/i>. belonging to the family Iridaceae (syn – kesar) comprises the dried red stigma and is widely cultivated in Iran and other countries such as India and Greece. Saffron contains more than 150 volatile and aroma-yielding compounds mainly terpenes, terpene alcohol, and their esters.<\/p>\n

https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3249922\/<\/a><\/p>\n

The Effect of Crocus sativus<\/i> L. and Its Constituents on Memory: Basic Studies and Clinical Applications<\/p>\n

Crocus sativus<\/i> L. (C. sativus<\/i>) is a perennial herb member of the Iridaceae family, the line of Liliaceae. This plant is cultivated in many countries such as Azerbaijan, China, France, Greece, Egypt, India, Iran, Israel, Italy, Mexico, Morocco, Spain, and Turkey. Its product is the well-known spice called saffron. Saffron, in filaments, is the dried dark-red stigmas of C. sativus<\/i> flower<\/p>\n

The potential role of saffron and crocin as adjunctive agents, in combination with an AChE inhibitor or memantine, for the treatment of memory disorders has not been investigated so far.<\/p>\n

https:\/\/www.hindawi.com\/journals\/ecam\/2015\/926284\/<\/a><\/p>\n

New insights into the biological properties of Crocus sativus<\/i> L.: chemical modifications, human monoamine oxidases inhibition and molecular modeling studies<\/p>\n

This study concludes that safranal and crocin represent useful leads for the discovery of novel hMAO inhibitors for the clinical management of psychiatric and neurodegenerative disorders.<\/p>\n

https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0223523414004723<\/a><\/p>\n

MEDICINAL USES AND PHARMACOLOGICAL PROPERTIES OF CROCUS SATIVUS LINN (SAFFRON)<\/b><\/p>\n

It has been demonstrated\u00a0 that crocin posseses antiapoptotic effects\u00a0 on\u00a0 non\u2010cancerous\u00a0 cells.\u00a0 Crocin\u00a0 suppresses\u00a0 cell\u00a0 death\u00a0 induced\u00a0 by tumour necrosis factor\u2010alpha\u00a0 (TNF\u2010\u03b1), cysteine protease mRNAs and simultaneously restores the\u00a0 cytokine\u2010induced reduction of TNF\u2010\u03b1 and mRNA expression6.\u00a0 U. Crocetin and haemorrahagic shock: Crocetin, a\u00a0 saffron\u2010derived\u00a0 carotenoid, was\u00a0 shown\u00a0 to improve\u00a0 post\u00a0 shock\u00a0 recovery\u00a0 of\u00a0 cellular\u00a0 adenosine\u00a0 triphosphate\u00a0 and\u00a0 to\u00a0 increase\u00a0 overall survival in an experimental model of hemorrhagic shock.\u00a0 In\u00a0 this\u00a0 model,\u00a0 crocetin\u00a0 caused\u00a0 the\u00a0 suppression\u00a0 and\u00a0 subsequent\u00a0 expression of messenger ribonucleic acid\u00a0 for\u00a0 tumor necrosis\u00a0 factor,\u00a0 interleukin\u20101 and inducible nitric oxide synthase44.\u00a0<\/b><\/p>\n

https:\/\/www.doc-developpement-durable.org\/file\/Culture\/Culture-epices\/safran\/M%C3%A9dical\/medicinal%20uses%20and%20pharmacological%20properties%20of%20crocus%20sativus.pdf<\/a><\/p>\n

Antidepressant properties of bioactive fractions from the extract of Crocus sativus<\/i> L.<\/p>\n

All these results suggest that the low polarity parts of <\/b>C. sativus<\/i><\/b> corms should be considered as a new plant material for curing depression, which merit further studies regarding antidepressive-like activities of chemical compounds isolated from the two fractions and mechanism of action.<\/b><\/p>\n

https:\/\/link.springer.com\/article\/10.1007\/s11418-009-0360-6<\/a><\/p>\n

Effects of saffron (Crocus sativus<\/i>) on sexual dysfunction among men and women: A systematic review and meta-analysis<\/p>\n

In general, saffron was proven effective in improving sexual dysfunction and its subscales among participants; this effect was different on different dimensions of sexual dysfunction.<\/p>\n

https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6727438\/<\/a><\/p>\n

Clinical evidence on the effects of saffron (Crocus sativus L.) on cardiovascular risk factors: A systematic review meta-analysis<\/p>\n

Present meta-analysis suggests that saffron might be beneficial in several outcomes related with cardiovascular disease.<\/p>\n

https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S1043661818316736<\/a><\/p>\n

Crocus sativus<\/i> restores dopaminergic and noradrenergic damages induced by lead in Meriones shawi:<\/i> A possible link with Parkinson\u2019s disease<\/p>\n

In this study, we have revealed a new pharmacological potential of Crocus sativus<\/i> that can be used as a neuroprotective product for neurodegenerative disorders, especially, which implying dopaminergic and noradrenergic injuries, like PD, triggered by heavy metals.<\/p>\n

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For more information call (800) 688-5956<\/span><\/b> or Contact Us for a Free Quote!<\/b><\/span><\/a><\/h3>\n

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[vc_row css=”.vc_custom_1641123265974{margin-top: 20px !important;}”][vc_column][vc_column_text css=”.vc_custom_1636972309949{margin-bottom: 0px !important;}”]Overview Description Affron\u00ae is a premium saffron ingredient standardized to 3.5% Lepticrosalides\u2122, which is responsible for the beneficial properties and organoleptic properties of affron\u00ae. … Affron\u00ae genuine quality relies on local trusted sourcing, the selection of the Spanish species Crocus sativus L. https:\/\/www.gencorpacific.com\/ingredients\/affron Saffron Crocus (Crocus Sativus) Benefits Saffron…<\/p>\n","protected":false},"author":6,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"content-type":"","footnotes":""},"_links":{"self":[{"href":"https:\/\/www.nutracapusa.com\/wp-json\/wp\/v2\/pages\/19346"}],"collection":[{"href":"https:\/\/www.nutracapusa.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.nutracapusa.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.nutracapusa.com\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.nutracapusa.com\/wp-json\/wp\/v2\/comments?post=19346"}],"version-history":[{"count":1,"href":"https:\/\/www.nutracapusa.com\/wp-json\/wp\/v2\/pages\/19346\/revisions"}],"predecessor-version":[{"id":19368,"href":"https:\/\/www.nutracapusa.com\/wp-json\/wp\/v2\/pages\/19346\/revisions\/19368"}],"wp:attachment":[{"href":"https:\/\/www.nutracapusa.com\/wp-json\/wp\/v2\/media?parent=19346"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}