Overview Description

Agarikon mushroom (Laricifomes officinalis) is also known as Fomitopsis officinalis, Fomes officinalis, Gharikon or Agharikon Has been in use for thousands of years world wide.

Due to its healing potential it has been recommended as a treatment against consumption illnesses such as pulmonary tuberculosis. It contains numerous active compounds, including agaric acid, carotenoids, fatty acids, vitamins, and more. Its primary use is as an antimicrobial agent, with potential antiviral and antibacterial properties. It may also be effective against some parasites.

Benefits and Uses

Agarikon mushroom is used to treat tuberculosis as it has strong anti-tuberculosis compounds, coumarines as antibacterial and lanostane triterpenoids as trypanocidal, in this mushroom.

It also has good anti-inflammatory properties that help in overcoming arthritis, joint pain, sciatica, and other inflammatory diseases and symptoms.

The compound which is a great antiviral agent is also found in Agarikon mushroom, molecules that are new to science.11 strains of Agarikon from North America were tested, and a few showed exceptionally strong activity against viruses including pox (cowpox), swine (H1N1) and bird (H5N1) flu, and herpes (HSV1, HSV2) viruses.

Antibacterial constituents have been found in Agarikon mushrooms which makes this fungus able to help fight infection.

Agarikon mushrooms also help to overcome pain and help reduce arthritis, lumbago, and other disease processes.

They are also considered to have benefits in treating kidney disease. If you consume Agarikon mushroom tea every day, this fungus will help overcome kidney infection, swelling, and other kidney problems.

Promotes circulation and may help overcome heart disease, stroke, poor circulation in the distal extremities and more.

Can relieve respiratory problems such as bronchitis, asthma, pneumonia, chronic cough, and other lung problems, by helping to open the lungs and get rid of mucus and swelling so you can breathe easier.

Beta-D-glucan and other polysaccharides are the compounds found in Agarikon mushrooms that work in helping to boost our immune system.

Agarikon mushrooms also have a role in improving interferon, T cells, interleukins, and tumor necrosis factors that all work against cancer.

Forms and Sources

Agarikon mushroom (Laricifomes officinalis)Grows on conifers, particularly Douglas-fir (Pseudotsuga) and larch (Larix).

Side Effects and Interactions

Agaricus products can cause blood sugar to go too low (hypoglycemia) in some people with diabetes. They can also cause itching, nausea, and diarrhea. A few people who took agaricus mushroom during treatment for cancer have developed severe liver damage, and a few have had allergic reactions.

How to Label

Agarikon mushroom (Laricifomes officinalis)extract

Research & Studies (References)

Antimicrobial properties of Fomitopsis officinalis in the light of its bioactive metabolites: a review

Fomitopsis officinalis, also known as Laricifomes officinalis, is a medicinal polypore used for millennia (Agarikon) to contrast several diseases, particularly the pulmonary ones.

A rich literature consistently confirms the existence of antimicrobial properties by F. officinalis, namely as antiviral, antibacterial and trypanocidal. Such an activity has been specifically recognised in a few molecules, e.g. coumarines as antibacterial and lanostane triterpenoids as trypanocidal, although most metabolites have not been singularly tested yet. The different range of metabolites in basidiome and mycelium is of major concern in assessing the antimicrobial potential as well as to manage the possible cultivation or harvest.


Anti-Oxidant and Anticancerous Effect of Fomitopsis officinalis (Vill. ex Fr. Bond. et Sing) Mushroom on Hepatocellular Carcinoma Cells In Vitro through NF-kB Pathway

This study assessed only one extract, Fo3-chloroformic, which has a significant impact on cancer cell lines.


Lanostane triterpenoids from Fomitopsis officinalis and their trypanocidal activity

The investigation of the chemical constituents of F. officinalis led to the isolation of 4 new lanostane triterpenoids together with 4 known triterpenoids. Inhibitory activity against Trypanosoma congolense, which causes fatal diseases in animals including livestock, was estimated for the isolated compounds.


Cytotoxicity of blended versus single medicinal mushroom extracts on human cancer cell lines: contribution of polyphenol and polysaccharide content

Blended mushroom extracts (Lentifom, Super Polyporin, Agarikon, Agarikon Plus, Agarikon.1, and Mykoprotect.)

These results reveal that these extracts exhibit different cytotoxic effects on tumor cells originating from different tissues. In addition, the comparison of investigated blended mushroom extracts with three well-known commercial mushroom products derived from single mushroom species or single mushroom compounds shows that blended mushroom extracts exhibit significantly stronger cytotoxic effects on human tumor cell lines.


Antitumor, Immunomodulatory and Antiangiogenic Efficacy of Medicinal Mushroom Extract Mixtures in Advanced Colorectal Cancer Animal Model

AGARIKON.1 and AGARIKON PLUS in various combinations with conventional cytostatic drug 5-fluorouracil in the advanced metastatic colorectal cancer mouse model CT26.WT. AGARIKON.1 and AGARIKON PLUS exhibited immunostimulatory and antiangiogenic properties in vivo which resulted in significantly increased survival and reduction in tumor volume.


Treatment With Medicinal Mushroom Extract Mixture Inhibits Translation and Reprograms Metabolism in Advanced Colorectal Cancer Animal Model as Evidenced by Tandem Mass Tags Proteomics Analysis

significantly improved survival, obtained results reveal that Agarikon.1 alone, and in combination with 5-fluorouracil exert their anticancer effects by affecting several fundamental processes important in CRC progression.


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